One thing you will notice immediately is that the battery life lasts much much longer. With casual surfing, watching video clips, playing casual games and Wifi always on, the battery lasts for almost 24 hours. It looks as if this is what the original Nexus 5 should be. All those background Google services and "frameworks" constantly calling back home will drain the battery to the death pretty fast. That's also valid for some other apps. Not having Facebook app installed will increase the battery life too.
Sure you have no Google Play store installed but you can always use one of those (safe) apk downloaders like Raccoon[1] or such to login to Play store and download your previous apps. As for other Google services (Maps, YouTube, Translate, GMail, etc.), I can always visit their sites in incognito mode. You will actually realize you really don't need all those individual apps to use these services. They all work good enough in a browser window.
[1] http://forum.xda-developers.com/showthread.php?t=1715375
I was feeling more and more dependent on one company's goodwill. A few months ago, I renewed my Fastmail [1] account for 3 more years, being very happy with the service. I use DuckDuckGo [2] as my main search engine and love it. I use Opera as my main browser. The only Google services I use regularly now are Android and YouTube. YouTube being totally optional and Android only being an interface to data located elsewhere, I feel free. Sure, Google has access to my data, but they can't lock me in.
[1] https://www.fastmail.com [2] https://duckduckgo.com