i can fully relate to this even though im the entrepreneur, but I can see the same happening with my wife. Sometimes it feels like living a completely separate life, different schedules. I think it can be managed, although it's hard. You need to set and dedicate personal / family time which you never sacrifice for meetings or work, and try to make each moment together same as it was on the honeymoon. it's damn hard, but otherwise the relationship wont work out, and you end up loosing everything, because when your going downhill emotionally which happens often in the startup life the only person who will support you AND ur company is your wife and no one else.