What blocker do you use that has decent blacklisting support? I tried a few some months back and went back to Ad Block Plus with whitelisting.
I'd rather blacklist though. I want to support sites that use unobtrusive advertising, but block ads on sites that use autoplaying videos, distracting animations, disgusting pictures of yellow teeth, etc.
I want to support sites that I consume content from, so by default I only block tracking beacons, not ads. I turn on content-blocking (or disable plug-ins/javascript) for specific sites when their ads make the site unusable. For example, nfl.com text articles used to not load for ages while video content loaded (it got better), and currently having the SF Chronicle open in one tab will make youtube stutter in other tabs.