Agenda for captured todos syncs with gcal. Publishing / printing to pdf / web / latex no problem. Index or search? No problem. Inline images and video, figured out. Snippet capture from web browser? Done.
Plus the incredible power to modify all this using emacs lisp. It's not python but it's powerful and every other emacs mode uses it.
There zillions of modes and tweaks to the emacs environment that add to this.
Org-mode and emacs are the single most powerful organizational tools I've ever encountered.
http://www.youtube.com/watch?v=1-dUkyn_fZA
And here are some more reviews, opinions, advices and experiences I just stumbled upon:
org-mode, while amazing, is emacs-only. There is no browser interface, no cloud (unless you store the files on Dropbox or GDrive or whatever) and no mobile app.
And that's its greatest failing in today's mobile/cloud world. Gee, it's almost like there's an opportunity here... ;)
Android app uses ssh, https://play.google.com/store/apps/details?id=com.matburt.mo...
iOS app uses dropbox, https://itunes.apple.com/us/app/mobileorg/id634225528?mt=8
Blog post on replacing other svcs/apps with org-mode, http://www.swaroopch.com/2013/01/16/orgmode/
Web bookmark sync on mobile, http://karl-voit.at/2014/08/10/bookmarks-with-orgmode/
There is a learning curve to be sure, but the payoff is incredible since you can then directly build research papers and books that output to LaTex/PDF....
Also, because Org files are at heart just some pretty simply formatted plain text, it would be easy enough to write Org entries in any simple text editor and add the file to your main Org repository of Org files at a later time, possibly by using the 'refile' functionality to have each entry in the "scratch" file routed to correct spot in permanent files.
I think Org-mode is probably one of the best knowledgebase solutions, but only for a limited range of users, who must be pretty savvy power users and also willing to devote a bit of time to get setup to their liking so they can then leverage it to their benefit. It's pretty hard to wrap your head around all the different things that Org-mode can do, and then a bit harder to create a workflow that's easy and fast to use. But many have done it, some for the knowledgebase scenario and some for the wide variety of things the very flexible Org-mode app can do.
My system is a tiny app that automatically grabs pretty much everything I do on the Internet and indexes it. Github stars, HN posts, Facebook likes, bookmarks, you name it.
I can optionally tag or add my own sticky-notes to anything, and there's some other neat tricks that make fuzzy searching a lot easier. Human memories are very story-based, and so if I only remember that I looked at something important about ducks when I was at a Meetup, I can actually search for that.
I'm considering productizing this -- email's in the profile if you'd like to chat. :)
On a side note, I use mizuno for a project[1] and I've never had any problems with it. Thanks!
That man has been trying to get traction on it since 1960. He's quite remarkable.
Actually, reading their blurb is like reading his work from then. If you know the story of Nelson and Xanadu, the lack of credit to him is a little unforgivable.
Inkling is working on related challenges with ebook authoring, https://www.inkling.com/blog/2014/06/problem-of-structured-a... .
InfinitePDF on iOS allows non-linear navigation paths to be overlaid on an existing PDF, http://www.148apps.com/reviews/infinite-pdf-review/
The challenge for all of these solutions is migration/import/rewrite of existing content.
Where Evernote falls down, and this is by design according to CEO Phil Libin, is in sharing across many people. Libin says Evernote is not social, it's anti-social. As such, it doesn't work when you need to collaborate on notes. But see Evernote Business which seems to contradict this assertion.
OP was talking about a personal solution so the social aspect doesn't apply.
I wish I had a solution.