The Art of Computer Programming is amazing. Its honestly one of the most difficult and impenetrable books you'll read, and that's being generous. That being said it is amazing. If you enjoy math and programming (and have post calculus mathematics skills) you can stumble your way though it mostly, it will be challenging.

But what you will learn even skipping parts, getting frustrated, coming back, leaving again. Is a lot. Knuth crams a lot of knowledge into, well a lot of pages.

Complete disclosure I have honestly haven't completely cover to covered every single volume. I skip around a lot.