Notes on the Synthesis of Form is a lot more systems-theoretic. The algorithm is more or less recursive min-cut partitioning which is now well-researched.

There is, however, a real logistical problem is getting the input requirements, massaging them to identical conceptual scope, and then connecting them together so you can perform said decomposition. That is a massive, massive bottleneck.

That's why it's so telling that Alexander abandoned the technique in his thesis in favour of using the building site itself, in effect, as a computational medium.