Most of those problems went away with the arrival of USB hubs. Granted, I still plug more cables than you do (monitor, sometimes audio). But I think for audio a USB solution could be found, too, then I would be down to three cables (monitor, usb hub, power). Sure, docking station is a bit faster, but it is also much uglier (most of the time). I guess it depends on how often you move around with your notebook.

I always work with an external monitor at home, but I use my notebook's keyboard. Atm I also only bother to plug in audio when I need it - I admit audio is a sore point, but when I have time, I'll try to find some wireless solution.