I'm assuming for a moment that you don't want to do research at Google or be a Senior Software Architect at a Fortune 10 company (both of which are still possible, though). For the majority of rote day-to-day programming gigs, even having a Bachelor's doesn't get you much over those who don't. Experience almost always trumps education in this field except for a few exceptions like those mentioned above. But you've got a leg up on those who don't have a degree - you've got one, it just doesn't happen to be in a relevant field. I was in your boat several years ago. My Political Science degree made it extremely hard to find a hiring manager/owner who was willing to take a chance. I did not have a github profile at the time (it was not that long ago) but I did have a website with some code on it (that my future employer did look at).

Just keep in mind that you will not command the same salary as someone with a relevant degree, at least until you have a portfolio of work comparable to theirs.