What other things have you tried? Did you try them rigorously (over a long period of time, comparing results with time periods where they weren't in use?) Did you try those things with the assistance or guidance of a professional?

Lifestyle changes, self-care techniques, antidepressants, dietary supplements, etc. are all things a medical professional will recommend to you - and the antidepressants are often the last thing they'll suggest. Did you try all of those, find them unhelpful, and resort to psychedelics?