Re:The brave new world of DIY faecal transplant
by micro_cam on Tuesday May 27, 2014 @12:07PM
(#7805161)
Fascinating. What are the symptoms or diagnostic tests that would lead a doctor to consider this?
Re:The brave new world of DIY faecal transplant
by giarc on Tuesday May 27, 2014 @12:51PM
(#7805394)
It would mostly be a parent investigating it on their own I would say.
It's well known that children with autism have frequent GI issues (diarrhea etc). You'll find that many parents have their autistic children on special diets (gluten free, dairy free etc) all of which attempt to alleviate the GI symptoms. They may work, but it's likely because they are changing the gut flora, rather than removing the gluten protein for example.
An interesting aside - as you may have read, FMT is being investigated as a treatment for autism. The thinking here is as follows. Babies are born with a certain level of Clostridium species (not necessarily C. diff). Clostridium are very good at producing toxins (botulism and the toxins involved in C.diff). Normally the level of clostridium in babies drops on its own. It's believed that in some babies, this drop never happens. These babies are then therefore continually exposed to toxins from these clostridium bugs, some of which may have neurotoxic properties and can result in autism. The goal of FMT is to alter the gut flora enough to get rid of these Clostridium species and stop the toxin from reaching the brain. There has been success in young children. What we need to keep in mind though is that autism is a spectrum of not only symptoms, but also a spectrum of causes as well, so FMT won't necessarily work for everyone.