The second element of the joke is that I presumed that HN readers, having a variety of esoteric hobbies, might also have an interest in cognitive science and linguistics (particularly the AI folks), and might want to analyze the brain of an outlier. I then decided that, while less accessible to a home hobbyist than brain surgery or in-depth psychological profiling, fMRI imaging conveyed the point of the joke in shorter, more recognizable wording, without actually being a very probable outcome.
In reality, you would probably be wired up to a home-made sensor array and presented with a series of time-indexed sensory inputs via headphones and a computer screen, and perhaps asked to press certain button sequences in response.
So, in short, no, those people do not need a fMRI. You, however.... I would like to analyze your physiological response to traditional comedy and contrast that with nerd jokes....