I second this. Chrome's multiple platform/profile feature is amazing [1]. I use it simply as as session manager [2] between work, personal, side-projects, etc. It greatly improved my development and browsing experience on the web.
[1] https://support.google.com/chrome/answer/2364824?hl=en
[2] http://scotch.io/bar-talk/leveraging-multiple-chrome-users-f...
I also use LastPass across profiles and 2-way auth for both LastPass and Google accounts.
If you want separate accounts just make one for YouTube (or whatever) then a separate one for Gmail.