On-Topic: Anything that good hackers would find
interesting. That includes more than hacking and startups.
If you had to reduce it to a sentence, the answer might be:
anything that gratifies one's intellectual curiosity.
Off-Topic: Most stories about politics, or crime, or
sports, unless they're evidence of some interesting new
phenomenon. Videos of pratfalls or disasters, or cute
animal pictures. If they'd cover it on TV news, it's
probably off-topic.
I feel stupid, but just don't get it. Why should I unfriend them for liking some rock band?