Small businesses, contractors, freelancers, and more who are asked to sign these are very much businesses and it is very anti-business to them.

It is relative, if you are big and established they are good, if you are small/medium (where most innovation and eventual businesses comes from) then they are bad.

It is anti fair business, but in a monopolistic/feudal/plutocratic type system it might be pro-business to own skilled people (anti-poaching agreements are also pro-business in that view). In a libertarian and free market sense it is anti-business when viewed from the aspect of an individual/small/mid company.

I guess its safer to say non-competes are pro big business and anti small business / anti innovation at least.