Re:The Full-Fat Paradox: Whole Milk May Keep Us Lean
by orjan on Wednesday February 12, 2014 @08:32AM
(#7224114)
I'm not a chemist so this was a bit difficult to parse for me. As I understand it, you're suggesting that the effect is not caused by the fat per se, but by some compound that is dissolved in the fat. Am I correct?
Re:The Full-Fat Paradox: Whole Milk May Keep Us Lean
by ifross on Wednesday February 12, 2014 @08:40AM
(#7224150)
I think the point was is that when the fat is removed from milk, it is not only fat that is removed, but also compounds that readily dissolve in fat.
This means that any effects seen could be due to the additional compounds as well as the fats that have been removed. I am not sure it is possible to distinguish what is the major cause for the effects seen.
Re:The Full-Fat Paradox: Whole Milk May Keep Us Lean
by orjan on Wednesday February 12, 2014 @08:43AM
(#7224171)
Thank you, that line of reasoning makes sense.
Re:The Full-Fat Paradox: Whole Milk May Keep Us Lean
by notacoward on Wednesday February 12, 2014 @08:46AM
(#7224192)
Not necessarily a substance already dissolved in the milk fat, but also potentially a substance already in other food or in the body itself that could be dissolved in the milk fat. A different kind of milk is going to have a different absorption profile, which could have interesting metabolic effects. While it's a bit counterintuitive that a higher-fat drink would be correlated to lower body fat, the body is a chaotic enough system that it's not entirely surprising.
So thats chemistry lesson 1, lesson 2 is "lots of stuff" in o-chem class prefers to partition itself in oil or water phase. So at least some ochem lab work involves a sep funnel which is a magic, yet simple, way to do liq vs liq extractions. Stuff moves from being dissolved in liq 1 to being dissolved in liq 2. Its a law of nature that its impossible for an undergrad lab involving a sep funnel to not have an accident or incident of some sort, usually more funny than dangerous. Not surprisingly one liquid is usually polar and one is usually non-polar because you can't do much of an extraction if liq 1 and liq 2 mix perfectly to create liq 3. And the sep fraction is often crazy, if you work the polar / nonpolar hard enough. I would imagine the sep fraction for salt or sugar in water/veg oil could be nearly a million, like the only salt in veg oil might be mechanical turbidity/suspension. Thats just a guess but I'm sure its ridiculously high if not a million. You can still have a "useful at lab scale" extraction if its only a factor of 2 or so, just pointing out its not shocking to be much higher.
Anyway the point of this chem discussion is there is no such thing as milk, there's a liquid that comes out of a cow and its got all kinds of crazy stuff in it, some of which STRONGLY partitions into either the polar or nonpolar phase. So the eventual discovery is probably going to be some kind of hormone, protein, mineral, herbicide, antiseptic, antibiotic, pesticide, solvent, "something" that strongly partitions / dissolves into fat and not into water. In the list above, hormones, herbicides, pesticides, and solvents tend to partition strongly into fat, the other stuff is a tough call one way or the other.
I would theorize that other animals living in the same contaminated conditions would partition the same way. Us mammals are not as biochemically different as some think. So its entirely possible you'd get the same effect from eating fatty meat, perhaps bacon, or foods cooked in (or made with) lard. Its worth some study.