I personally hate the idea of drivers wearing these things. My undergraduate was in psychology, neurophysiology, and hence I've been formally trained in attention and perception - I've got a better idea than layfolk on how these are compromised, though I'm not a professional in the field. In my opinion, the Glass is a significant attentional split - which is bad for driving. One example: say voice control is working fine (it doesn't always). You still have to take your eyes off the road, target a small reticle, make sure the glass is responding correctly. Even after that, there's still issues like just having a phone call in the car, which regardless of the device is a driving-performance-reducing attentional split.
Glass really, really impresses me as a technological feat; as a product I think it's a solution looking for a problem; and as a social phenomenon, I think it's quite dangerous when mixed with common activities like driving.
Think about the avg hourly commute to work - how useful would it be if that time could be used for something else!
If you're wearing Glass properly, the screen is also up at an angle above your eye. If you're sitting in the driver's seat of a vehicle and looking forward, the display would be about at the area where your sun visor would be if it were flipped down over the top of your windshield.
I suspect that Glass would beat out the Garmins and Tomtoms.