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Re:Calorie restrictive eating for longer life? The story we ... by anamax on Monday July 13, 2009 @09:43AM (#701665)
> There is no reason to suppose that dying under anesthesia is related to the diet.

If monkeys in one group were more likely to die under anesthesia than monkeys in a different group, I'd suspect that something is going on. (Being unimaginative, I'd exclude the possibility that dying under anesthesia causes a low calorie diet.)

Re:Calorie restrictive eating for longer life? The story we ... by Confusion on Monday July 13, 2009 @11:35AM (#701894)
If two monkeys in one group died under anesthesia, that doesn't constitute ground to conclude they were more likely to die: it is simply not statistically significant. Hence you may subtract them from the age related deaths.
Re:Calorie restrictive eating for longer life? The story we ... by anamax on Monday July 13, 2009 @10:06PM (#702959)
> If two monkeys in one group died under anesthesia, that doesn't constitute ground to conclude they were more likely to die

I didn't say that two monkeys constituted statistical significance.

> Hence you may subtract them from the age related deaths.

You can subtract them because they're not statistically significant, but you can't conclude that there isn't something going on, which is what "there's no reason to suppose" means.

Suppose that odds of death due to anesthesia is really low (which it is) but that calorie restriction increased it by 10x (which we don't know either way). 10x a really small number is small enough that this study can't observe the effect because it doesn't kill enough monkeys. And yet, that 10x can easily cause two deaths in one pool while the other has 0.