The real problem, though, is that this represents an extreme upper limit on the effect that the nuclear weapon would have. Since most of a nuclear weapon's energy is in the initial impulse, most of it will pass through the hurricane with no effect whatsoever.
Another point to consider is we can try to use a nuclear explosion in order to prevent a hurricane from forming if we catch it early enough. Is that possible?
I do doubt that we can routinely nuke hurricanes (even ignoring the radiation effects), but looking at just the mechanical effects, I think it would be interesting to take another look at the picture. I am not sure that the effects of turbulence can be calculated, but how much can we get from the first principles?
BTW, Hiroshima was about 15 kt, if I am not mistaken, and the average modern nuke is on the order of 400 kt.
Now let's see. First, there is a question of what effect it would have. How powerful should a nuke be in order to actually destroy a medium sized hurricane, and how will it affect the atmosphere and biosphere and the earth surface near the epicenter? Second, what should we do with the nuclear fallout? I am sure there are more questions to ask.