Though, as far as one can predict, I bet determination is the best indicator we can hope for.
You can probably say with some degree of certainty, which people won't do anything big. That might still leave a pretty large group of people, though.
Who else thinks it would be a lot of fun to see a Graham-Taleb debate on startups? In the end, I think he'd probably like what YC does, because you're giving some people the freedom to "tinker" full time, along with the support to take advantage of the tinkering if it produces something cool. Given a non-infinite supply of money and attention time, of course you're going to have to pick and choose who gets those things. I wonder if he would suggest any changes to the format?
For example, a person applies to YC. They get rejected and use that as incredible motivation to succeed in spite of that. If they had been selected, would they still have had that motivation?
"The only bad news is that we can't really tell where the good news are going to be about, except that we can locate it in specific locations, those with a high number of trials. More tinkering equals more Black Swans. Go look for the tinkerers."
http://edge.org/q2007/q07_5.html#taleb
The Forbes article is basically just the edge answer minus a few paragraphs, although sadly the paragraphs that got cut were the ones that would probably be most interesting to YC types.
http://paulbuchheit.blogspot.com/2007/03/how-to-be-right-90-...
One reason that applicants should not take rejection personally is that YC would be wasting time trying to evaluate them with 100% accuracy.
I'm not so sure about this. I'd rather like to think: All the people who have taken credit for stuff that has changed the word have been energetic and determined.
I agree with this essay, but I don't think the title is quite right. All the people who've changed the world have been energetic and determined. So you can to some extent predict by recognizing those qualities. You can predict the people, just not what the ideas will turn out to be. The title should have been "You can't predict how the world will change."