The qualification of "worthwhile" is really subjective to the point where unless you're literally doing something truly impactful (which I define as value + massive scale, e.g., cure to cancer, etc.), your value is at best a surface scratch and at worst a fad.
Consumer oriented startups like Snapchat spring to mind, which seems to have both a questionable mission statement + a shameless pursuit of founder enrichment. Not judging (I'm jelly), but I do think it serves the greater point I'm trying to make.
Of course, making money is also important, if only because money allows us to hire better people and do a better job, and it was also a primary reason of starting GrantTree... but it's not a good enough reason to put all the energy to grow it past the stage where it is an extremely profitable hobby, to the stage where it is a genuine business.
The company should have an objective to do something good and worthwhile for people outside of the business. Even "lifestyle businesses", whatever they may be, should.
All three are fundamentally necessary, sine-qua-non: making money, doing something worthwhile, and doing it in a way that builds people up rather than grinding them down.