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Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by PaulHoule on Friday October 18, 2013 @08:30PM (#6574807)
Why is it always cancer?

I'd be impressed if somebody was trying to cure ALS or Tourette's syndrome.

Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by teraflop on Friday October 18, 2013 @09:21PM (#6574937)
Maybe because cancer is ridiculously more common than both of those disorders combined?
Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by PaulHoule on Friday October 18, 2013 @09:23PM (#6574941)
Perhaps cancer in general, but not particularly types of cancer, when you recognize that there are multiple forms of lung cancer, breast cancer, etc. -- common forms of cancer are not a single disease.

The trouble with cancer drugs is that you take them for a short time and you either die or you survive.

The real money is in drugs that a large segment of the population can take for an indefinite time such as Lipitor, blood pressure meds, asthma inhalers, and the perpetually elusive obesity cure.

Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by thaumasiotes on Saturday October 19, 2013 @04:06AM (#6575737)
Sure, but obviously curing cancer is a waste of research effort... what they should be trying to cure is disease.
Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by foobarbazqux on Saturday October 19, 2013 @04:18AM (#6575759)
Why is it a waste of research effort? We've made dramatic non-palliative strides in the area of cancer treatment, and most importantly have been able to induce complete remission in a significant number of cases.
Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by thaumasiotes on Saturday October 19, 2013 @04:41AM (#6575806)
see my sibling comment.
Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by foobarbazqux on Saturday October 19, 2013 @02:08PM (#6577227)
Sorry, I don't understand. If you meant PaulHoule's comment I'm not sure how that answers my question, and I didn't find any other comments by you. Do you mean because cancer isn't a simple, isolated thing like polio or TB?
Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by thaumasiotes on Saturday October 19, 2013 @08:03PM (#6578458)
Yes, I meant PaulHoule's comment. If the reason for studying "cancer" is that "cancer" is more widespread than better-defined illnesses, then the reasoning is misplaced; it's surely better to focus on something more widespread, like "illness".

I have seen it expressed, though not in these terms, that asking for a "cure for cancer" is equivalent to asking for bug-free software. Cancer isn't something that afflicts you from without; it's just a failure mode for cells. They can fail for all kinds of reasons (indeed, note that one of our best methods of causing cancer, radiation, works on the principle of "make random changes to the cell's genetic code, and it will eventually become cancerous").

Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by foobarbazqux on Sunday October 20, 2013 @02:34AM (#6579112)
So I think the general claim is that focusing on cancer is a middle ground between seeking treatments for obscure well-defined illnesses and searching for a panacea for illness or disease in general. Cancer has a precise operational definition: unregulated cell growth. It isn't nearly as vague as illness or disease. We understand a lot about all the different pathways inside cells that can lead to it. A "cure for cancer" is an attempt to address the issue upstream, such that it will affect all different types of cancer in the body. Unlike seeking a panacea for all illness, this is not obviously a waste of research effort. There are highly similar mechanisms at work in every cancer. Even if a cure-all cannot be found (I would be surprised, personally), just trying to understand the mechanisms still has value.
Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by thaumasiotes on Monday October 21, 2013 @12:01AM (#6583249)
Actually, a cyst meets your definition of unregulated cell growth. It's just slower / less greedy. The distinction between a benign tumor and a malignant one is generally ascertained by the process of "let's watch it and see what it does", so I'm not convinced that "cancer" is defined more usefully than "illness".

In my opinion, and my medically-educated mother's opinion (really, I get it from her), people don't look for "a cure for cancer" because they think they can make progress from that viewpoint. They do it because they're looking for funding.

edit:

You might compare "died of cancer" to "died of old age". Old age used to be an accepted cause of death. When autopsies started happening, it was quickly noticed that people who had died of "old age" always had some other, more immediate cause of death. But it turns out that if you take an old person and do your utmost to prevent / cure / treat all of those more proximate causes, eventually one will get past you and they will die.

Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by foobarbazqux on Monday October 21, 2013 @01:35PM (#6586983)
Okay, but that's not actually how cysts work if you look it up. They are sacs that can have cancerous tissue inside them, but they can also have fluid or air. The operational definition of benign and malignant tumors that doctors use boils down to rudimentary observation, yes, but in the lab we've really identified many of the key mutations in the transition from benign to malignant. So I guess you could say we have a reasonably good idea of what cancer is and how it works, but it hasn't fully made its way onto the front lines yet, either in terms of assessment or treatment.

I understand your cynical point of view about funding, but I guess I would say two things. First, cynicism is a cancer unto itself (ha), and all academics are faced with the corrupting influence of money. Second, if you go and talk to the cancer researchers in the nearest university you'll probably find a great deal of them really do care about the work; they just might care about a very tiny corner of it rather than a cure-all solution.

Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by hershel on Saturday October 19, 2013 @07:56AM (#6576091)
In this case they choose cancer , because

1.It's a large field, plenty of money.

2.Genetic/molecular cancer medicine is advancing rapidly, creating tons of data, which means This field will most likely be highly computerized anyway.

3.Machine learning is the core of genetic cancer medicine , and a lot of data could be really helpful.

4.Assuming this is the best approach to to do cancer medicine ,watson will have strong political allies on his side , since cancer frightens everyone , including powerfull people.

Re:IBM Watson fires its own cancer-fighting ‘moonshot’ by GalacticDomin8r on Friday October 18, 2013 @11:04PM (#6575162)
> Why is it always cancer?

I guess your mother and your grandfather and your first cousin didn't die of cancer. Very difficult to find that situation even combining ALS, MLS, Parkinson's, and Tourette's syndrome.

Maybe some day Watson can cure the most deadly disease of all -- idiocy.