This. There is only one Limbo, Gish, Fez, Galcon, Voxatron etc.
Ending a list of one-of-a-kind things with 'etc.' somewhat undermines your point.
Each is special in their own sub-(sub-)genre niche. You can't expect making a quality Angry Birds clone and be hugely successful. Now cross it with some other game and you might be on to something.
You still need to make a game that is playable, has replay value, engages the person and is fun to play. That is no easy task at all.
Some have the gift for it and for those this is an incredible opportunity. I look at Temple Run and Ting Wings on iOS. Two games that stand out for their uniqueness and that were developed by 1 or 2 people.
No one is getting anywhere making another Tetris clone or a match 3 game unless there is really unique twist to the game.
At the end of the day, the tools are much much better but you still need that gift to know what will click with people.