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Re:LSD microdosing: a randomized, blind self-experiment by lsd_dose_ta on Thursday October 17, 2013 @12:31PM (#6566408)
Exactly. Even within a single sheet, the dose per "tab" can vary. Outside of that, even from the same vendor, the dose might vary by a factor of 5. The only remotely reliable method is to take enough to be psychoactive, then wait a week and take it again, trying to hit the point where you have threshold effects (a binary search over dosing strength). Even then you might be off on your dose guessing be 30% or more.

He may have gotten far less LSD than he believes.

Re:LSD microdosing: a randomized, blind self-experiment by gwern on Thursday October 17, 2013 @05:07PM (#6568131)
> He may have gotten far less LSD than he believes.

Or more. In the absence of any reason to believe one direction, the expectation of the shift is zero...

Re:LSD microdosing: a randomized, blind self-experiment by MichaelGG on Thursday October 17, 2013 @10:12PM (#6569395)
In general, why would a vendor sell more of any drug? I'd think that getting undersold is far more common than getting free product.
Re:LSD microdosing: a randomized, blind self-experiment by gwern on Thursday October 17, 2013 @11:27PM (#6569602)
That's different from saying that the layer's product can vary from tab to tab.