I use my touchpad with the native DPI, which is not officially supported, and never had any problem with app compatibility due to the screen... but i don't use many apps.

mostly browsing.

Also, i'm on CM9. which is android 4.0 something. The last thing that didn't work and was holding me on CM7 is the camera. It's working now. CM10, android 4.2 is coming and the reports are good, but it is a work in progress. That said. There is ZERO features i want from 4.2. OTH, CM7 and 9 have a feature where i can limit which permissions the APP is allowed to use at runtime. and other niceties such as render effects, etc. noted, all available on all androids, but not exposed as options to the user. because users are dumb or something and can't have options.