SJCL is good software and has good defaults for its high-level encrypt function `sjcl.json.encrypt`. It uses CCM so you don't have to MAC in addition to encrypting (as TripleSec does). Depending on what parameters and degree of safety you want for PBKDF2, you might wind up locking up the browser while your keys are being derived. It's hard to speed up this part of the encryption process because it's meant to be intentionally slow to prevent password cracking.

The biggest problem you'll have in building a secure chat app is establishing the connection in the first place. To do that, either the participants will have to share a secret, or there will have to be some sort of public-key based handshakes with certified public keys.