Lisp-2 is much saner. What it adds is just funcall, and it's not such a big deal in practice, because most of the times in the situations of higher-order function you would use apply, reduce or map, which likewise should be used in Lisp-1. What it brings instead is that you have to worry about name clashes much much less. The classic is list vs lst.

What I personally like is that you always know what are you referring to in a higher-order function call: a variable name or a function name. So it just removes the need for some additional intellectual effort of remembering this (i.e. #' is a nice annotation)