Calories and fat have been the go-to for mainstream publications as the cause of obesity. But I'd highly recommend watching this talk about high-fructose corn syrup:

https://www.youtube.com/watch?v=dBnniua6-oM

It makes a great argument that high-fructose corn syrup might be single handily the cause of the explosion in obesity in the USA in the last two decades.

I know this video and he's wrong (HFCS is bad, simple sugar and fruit fructose are not). I would recommend you to read articles on http://dannyroddy.com http://raypeat.com http://andrewkimblog.com backed by a lot of studies showing fructose is awesome.

I'm appalled by your lack of judgment.

You dismiss the recording of a university class made by a Ph.D in Endocrinology that worked for 20+ years against the whole industry (which shows resilience and belief).

On the other hand you suggest to read articles on 3 websites that looks scammy at best?

I feel insulted.

I could return the compliment.

And I'm not saying he's wrong, I'm saying HFCS is indeed toxic, not sugar and fructose (proven by lots of studies made by PhDs with years of experience). So he's partially right.

Stephan Guyenet is a phd and he also kinda poo-poos the whole "sugar and fructose are toxic" thing. The problem with fructose is just that it's so yummy to humans that its modern ubiquity causes people to overeat.

Obviously his theory is being challenged and there might be some valid reason why it is. I'm not an expert in that field.

The guy saying Lustig is "wrong" was just full of it and I called him on that.

"feeling great" != healthy; "not fat" != healthy

A calorie isn't a calorie. The impact that 100 calories of vodka has on your body vs, say, 100 calories of Kale is significant. The body uses different strategies to break down different types of molecules. There can be toxins. There can be impact on the gut flora. Not to mention the impact that these all have on the feeling of "fullness" (which the article mentions).

If you prefer I've never been that healthy in my life. Every health marker is green.

You are grossly oversimplifying a complicated process of digesting food and its interaction with the overal metabolism of the body. Yes, calories play a factor, but also in what form you ingest them. Then there's genetic factors, gut bacteria, physical exercise and probably a whole slew of other things that interact with each other.

The article oversimplify the topic too. Saying that fructose is bad is oversimplying the reality.

Metabolism plays a very important role and even if it's really complex, fructose is very good for the metabolism (glucose is inferior in that regard).