I've started doing my academic writing in MultiMarkdown (MMD) using Scrivener. It generates LaTex (or PDFs via LaTex) and for me is even easier than Lyx. When needed, you just embed raw LaTex in the doc as <!--xxx-> comments or just do the final polishing in your usual LaTex editor.

I almost forced the team to choose Markdown, and then had to change my advice and say "Let's go with LaTex" because there are so many features MS Word users want to use... I don't remember exactly the one that prompted the switch - maybe footnotes, tables or referencing.

Have a look at ConTeX (www.contextgarden.net). It is a TeX macro package, just like LaTeX. But it is a MUCH more consistent syntax, heavily relies on LuaTeX, and can generate XML output (for webpage and epub) as well.

Try LyX. Nothing comes close to math in latex

Seriously, you will regret not using TexStudio, I guided a friend who installed it on Windows (works on Mac,Linux too) and damnit, it can transform drawings of formulas or anything to LaTeX-Code. That's awesome!

TexStudio, no thanks, it has no WYSIWYM editor, I can't format tables like that.

It has a table-assistant, a matrix assistant etc., but you decide.