Re:Down syndrome reversed in newborn mice with single injection
by epo on Thursday September 05, 2013 @12:35PM
(#6335125)
They did not build DS into mice, they created one of its symptoms which they then reversed, hence my comparison to exaggerating the effects of sticking plasters. The mice did not have anything like DS and claiming this experiment as having anything to do with DS is sensationalist exaggeration, in fact it is borderline dishonest.
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Re:Down syndrome reversed in newborn mice with single injection
by topynate on Thursday September 05, 2013 @12:40PM
(#6335154)
So what would be required for the mice to have something sufficiently Down's-like? They didn't shrink the brains with toxins or anything, that shrinkage was a natural consequence of duplication of genes, just as it is in human DS.
Re:Down syndrome reversed in newborn mice with single injection
by epo on Thursday September 05, 2013 @12:50PM
(#6335229)
Some genes, not all of them. The experiment was about brain shrinkage, not Down's syndrome.
Re:Down syndrome reversed in newborn mice with single injection
by vilhelm_s on Thursday September 05, 2013 @01:06PM
(#6335360)
The mice are made specifically as an animal model of Down syndrome. See http://dmm.biologists.org/content/4/5/596.full