I run a site that makes its money from ads, and I personally have no problem with people blocking them. I figure the people blocking them are less likely to click anyways, so I'm not too concerned. Obviously it would be a problem if everyone blocked ads, but I think that is pretty far off.

Example: I only bother to block them on my main computer, but don't on my phone, desktop, etc. Your average Joe is unlikely to start doing so soon.