Not in an insurgency, low-intensity warfare sort of way. Not unless you can somehow make them very targeted.

"We had to destroy the [village] in order to save it" doesn't really apply if you consider, say, New York City.

As https://en.wikipedia.org/wiki/Millennium_Challenge_2002 (and, of course, successful terrorist acts over the last decade) demonstrated, low tech is still Good Enough for a lot of purposes.

Exactly. It's guerilla warfare. The military would be next to useless in a situation like that. Not to mention morale issues.

Yes, but that's assuming there are people in the government with the will to deploy those weapons against the public. At best they'd only achieve pyrrhic victory.