That's hyperbolic. If 100 people took LSD, some would be negatively affected, some would have life-changing experiences, and most would just experience some profundity and hallucinations. I think even for them it would be life-changing, but not on the order of, say, being in an auto accident, or running a marathon, or raising a child.

People call these things "trips", and I'd say that's about right. (I haven't taken LSD, but have taken psylocibin which is milder.) An extended trip, vagabonding without a goal, going new places and meeting new people, without "pushing" to make things happen, is similar to a "psychedelic" experience. It is profound.

I wouldn't recommend using LSD. I'd recommend using a milder drug like psylocibin, or maybe mescaline extracted from a farmed San Pedro cactus. (Don't go after the peyote - it's going to go extinct.)

Also, I would suggest waiting until you're in your early 20s to 30s, and if possible, not using any alcohol or other drugs prior to it; I think it makes it harder to notice the dosage as its taking effect.

It's been around 20 years since I've last had a trip, but it affected me a lot and made me a less judgmental person. I did eat some around 10 years ago, but it was a tiny amount and had only a mild effect; but having curtailed drinking, it was a much better experience.

I do not know where to get these drugs now, nor am I interested in obtaining any.

Also, if you want a profound experience without chemicals, travel if you can afford it. Do some work with people who have difficulties in life. Work a physical job that leaves you exhausted. Teach something to someone who cannot learn a subject you find easy. If you put yourself in a situation where you're not only helping others, but allowing others to help you, you will have profound experiences often.