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A comment on Mac Pro. Parent comment
As far as 16GB dimms in standard sizes; that's already a thing: http://www.newegg.com/Product/ProductList.aspx?Submit=ENE&N=...
There are also a handful of 32GB DIMMs out already. Example: http://www.newegg.com/Product/Product.aspx?Item=N82E16820326...
I would expect that you'll be able to run 64 or 128GB of RAM max.
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As far as 16GB dimms in standard sizes; that's already a thing: http://www.newegg.com/Product/ProductList.aspx?Submit=ENE&N=...
There are also a handful of 32GB DIMMs out already. Example: http://www.newegg.com/Product/Product.aspx?Item=N82E16820326...
I would expect that you'll be able to run 64 or 128GB of RAM max.