Look at how EMC does it. Almost no software companies they bought have really flourished. Smarts, Infra, Voyence, nLayers, Configuresoft and Fastscale are to name just a few. All are on the way out, or are so ridiculously unsuccesful compared to when they were nimble and smaller.

If you get acquired by a monolith, then don't expect the acquisition to succeed. It will most likely fail.