You can do it while following a similar approach to what is done for PythonScript, it's easy. PythonScript is compiled to Javascript, it use the Python abstract syntax tree module to parse python code then generate javascript. The subset of python that is (directly) translated to Javascript is PythonJS. With PythonJS is implemented some runtime stuff and higher level construct of Python. http://apppyjs.appspot.com/ Sorry the editor is broken.