There's no known physical risks to using DMT. It is naturally produced by your body in small amounts.
The risk is integrating the experience of traveling to another "dimension" and then coming back to reality. If you aren't psychologically fit, you shouldn't try it. But mostly it will feel like a dream. Hard to believe it happened and impossible to explain.
Re:Why We'll Never Meet Aliens
by baron_mango on Friday May 03, 2013 @07:43PM
(#5653306)
https://www.erowid.org/columns/teafaerie/2012/01/19/ymmv-201...
Do your homework. Know yourself, know your substance, know your source - then pay attention to your [mind]set and setting.
Change yourself at your own risk.