certainly, and I didn't intend to minimize it, just to highlight the lack of awareness of the deleterious effects of prostate cancer treatments given the oft cited sense of disfigurement from mastectomies. both are terrible for the patient.

It is also possible that due to a mastectomy menopause onset is accelerated.

I wasn't familiar with that. Is that stress-related? Mastectomy without chemo should not induce menopause, as far as I understand the physiological processes at work. If the patients are also being treated with tamoxifen or other estrogen receptor antagonists then the menopause is, I believe, reversible.