Gerrymandering is a serious problem, but it just changes the tactics necessary to win: Instead of spreading out nationwide to try to change the result in every individual district, we concentrate on the districts with contested seats. And because those seats determine who gets the majority in the legislature, if you can cause a substantial number of votes to change sides in those districts based on the party's stance on your issue, you can influence the party's platform -- or deprive them of the 51st vote necessary to pass legislation contrary to our interests, because the representative from the contested district can't vote against us without it costing the next election.

In addition to that, gerrymandering just pushes the real campaign into the primaries for those seats. If your representative's party has a hard lock on your district's seat, do what the Tea Party has been doing and primary the incumbent. And fewer people vote in the primaries, so each vote you can shift from one candidate to another counts for more there.