If you mean Overly Attached Girlfriend [1], she framed the joke intentionally, in terms of its visual look and its connotations, in exactly the form that took hold as a meme.

Contrast this with memes where a picture caught the eye of a photoshopper who then decided what joke to write on top.

It was her own sense of humor from the start. Good on her :)

[1] http://knowyourmeme.com/memes/overly-attached-girlfriend