The generalized protocol/URL idea is a nice one. I'm not sure it'd be simpler, but it'd certainly be useful.
It's interesting you mention AMQP; this work I'm doing actually came out of some of the work I did as part of my work on RabbitMQ.
Ah, you work at LShift. A funny coincidence indeed.
I think the URL request protocol itself would be fairly simple but any use case would be application specific so coming up with a general purpose implementation might be tricky.
I'm just finishing off the Erlang book and for my first project, I was going to either build a general purpose Comet server (improving on Orbited, Meteor, cometd, etc) or flesh out the above protocol and implement it... or a combination of the two. If you want to offer input or be involved: jedediah at silencegreys dawt kom.
This is just off the top of my head and there are surely better approaches but the point is that it's quite doable and probably as simple or simpler than something at the HTTP layer.
HTTP's "richness" is also what makes it a pain in the ass. It's a megalomaniacal protocol designed for a very specific purpose and when you are forced to use it for any other purpose, you have to carry a lot of baggage, and the baggage is full of rocks.
This gateway service is nearly always going to be used to create some sort of ad-hoc messaging endpoint, rather than a proper web server with web pages, so why force tunneling over TWO layers of HTTP while precluding the use of any existing wire-level level protocols?
It's time we buried the "use HTTP for everything" meme. We already have an everything protocol called TCP and if there's going to be a layer after that, it will be a carefully designed, flexible messaging protocol like AMQP. HTTP adds negative value as a general purpose transport and it's not even that great for serving web sites.