When you're getting ready to do massive runs, yes, you want to make sure your ICs are common, have pin-equivalent drop in replacements, and can be sourced from a reliable distributor. But that's not the point since such a run would take weeks or months anyway, more than enough time to properly source everything.

However, there's still no "3d printer equivalent" for electronics prototyping especially when using BGAs.

I've paid way more than $65 for overnight shipping from Digikey, Mouser, Arrow NAC, etc. Especially when ordering from multiple distributors (for some reason it always seems that my kits end up being a 90:10 split between Digikey:Mouser).