In general my personal research thesis is that current deep learning is much less malleable and neuroplastic as it should be, I got into interpretability because of this. Many focus on safety, but I prioritize it as a toolbox that allows for greater shaping of the underlying intelligence system. If we can fully understand how learning happens, where information is stored and how it is processed, unlike in biological brains, we can apply edits and transformations in digital ones. And if I can use a technique to edit weights based on some underlying reasoning about a system (with a caveat that it leads to something worthwhile), so can an agent. Hence self-improvement. There are many interesting implication to weight space research, and I very much encourage people to read about it. But it is also very easy to overstate what is currently possible, in fact I'd say better to know what is not so one can make it possible.
Why do you think this is? I am very new to this research, but to me, the biggest challenge appears to be how information seems to be stored in superposition (making it difficult to change one thing without affecting others). But biological brains appear to exhibit the same kind of superposition storage as well, and yet they are very plastic.
My guess would be that the structure to allow for plasticity to work is a strong limit to how well you can tune weights to fit training data. My (doubtless massively oversimplified and way behind the state-of-the art) understanding of neuro-plasticity is something like "often used pathways get stronger connections". Which, even with significant tweaks, is quite different from the gradient descent used to tune neural networks.
It argues that our understanding of neurons storing information in superposition was just a limitation of our tools and us thinking about it wrong. Instead most neurons initially specialize, and then branch out into related concepts. In addition, understanding one part of the network helps better understand other parts. And with agents we can scale this to understand non-trivial networks.
While, if true, this would more directly help with interpretability, a better understanding could also help with improving NNs in general.
I'm reminded of how humanity recently finished mapping out the fruit fly connectome; this does not put us meaningfully closer to, say, doing surgery on humans to cure schizophrenia.