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Re:Claude discovers a novel enzyme system with CRISPR-like r... by yunyu on Wednesday September 23, 2026 @07:08PM (#49823909)
It's pretty clear reading from these comments that most HN members have a 2023-era impression of LLMs.

Modern chain-of-thought models with RL post training on verifiable tasks + realistic environments + rubrics are worlds apart from models trained on a simple next token prediction objective.

More money goes into the rubrics and RL environments than individual training runs themselves.

(Yes, at inference-time LLMs still output words one at a time, much like human speakers. But don't confuse the mechanism with the training objective.)

[dead]
Re:Claude discovers a novel enzyme system with CRISPR-like r... by solenoid0937 on Wednesday September 23, 2026 @10:31PM (#49825494)
> and a single hallucinated token can still derail the entire chain of thought.

Incorrect. As the OP said, that is a very 2023 understanding of how LLMs work.

Grab a new model from OpenRouter. Have it work on a task. Change a few tokens and have it continue the completion.

Re:Claude discovers a novel enzyme system with CRISPR-like r... by geraneum on Thursday September 24, 2026 @02:12AM (#49826843)
> Have it work on a task.

With or without a harness?

Have you actually tried this yourself? Of course it can derail it. Try to reflect on your interactions with LLMs without all the constraints like web search, agentic scaffolding, etc.

The same way that a “yes” or a “no” input from you can change the response, cot tokens are fed back into the model as input and can derail it.

Re:Claude discovers a novel enzyme system with CRISPR-like r... by user43928 on Thursday September 24, 2026 @03:50AM (#49827569)
Have you? Can you show such a derailment with a large SOTA model?

It would be interesting.

I have seen such derailments within the GHCP harness maybe with GPT 5.6 Luna that went into some loop about whether it already provided a final response to the user, or 5.6 Sol suddenly switching to talking about MS SQL performance.

I also saw a post about Sonnet unexpectedly talking about Minecraft after seeing a file with a related name. The user thought it was the output of another user's conversation so the post was fairly popular.

Re:Claude discovers a novel enzyme system with CRISPR-like r... by geraneum on Thursday September 24, 2026 @06:24AM (#49828601)
> Harness… seeing a file…

Thank you for making my point for me. But let’s keep the goalposts stationary. We’re talking about LLMs without scaffolding.

Re:Claude discovers a novel enzyme system with CRISPR-like r... by user43928 on Thursday September 24, 2026 @08:45AM (#49829841)
Indeed, and it would be interesting whether it is much more likely to derail outside of a coding harness like in my examples.

I still don't know if that is the case, and how frequently it happens, since you did not share details beyond vaguely suggesting it would happen.

Re:Claude discovers a novel enzyme system with CRISPR-like r... by solenoid0937 on Thursday September 24, 2026 @08:37AM (#49829760)
Without a harness. Yes, I just tried this on OpenRouter.
Re:Claude discovers a novel enzyme system with CRISPR-like r... by geraneum on Thursday September 24, 2026 @08:54AM (#49829917)
What did you try exactly?
Re:Claude discovers a novel enzyme system with CRISPR-like r... by yunyu on Wednesday September 23, 2026 @10:44PM (#49825581)
When you speak or type, you speak one word at a time. When you move, you actuate one muscle at a time.

Does this mean that a single incorrect word or twitch will completely derail the task you’re trying to performance? Or will you, like any other intelligent being, recognize it and compensate?

Re:Claude discovers a novel enzyme system with CRISPR-like r... by geraneum on Thursday September 24, 2026 @01:58AM (#49826747)
Analogies are good for conveying meanings not proving statements. How human muscles or brain works has no bearing on LLMs.
Re:Claude discovers a novel enzyme system with CRISPR-like r... by Marha01 on Thursday September 24, 2026 @12:47AM (#49826370)
> Take away the heavy agentic scaffolding and external feedback loops, and a single hallucinated token can still derail the entire chain of thought.

With reasoning models, a derailed chain of thought can be rerailed.

Re:Claude discovers a novel enzyme system with CRISPR-like r... by geraneum on Thursday September 24, 2026 @01:59AM (#49826756)
> can be rerailed

What rerails it?

Re:Claude discovers a novel enzyme system with CRISPR-like r... by Marha01 on Thursday September 24, 2026 @10:54AM (#49831495)
The model can realize it made a mistake earlier and correct itself in subsequent output. I have seen it happen many times in CoT.
Re:Claude discovers a novel enzyme system with CRISPR-like r... by geraneum on Thursday September 24, 2026 @02:23PM (#49834797)
That’s the point. It may or may not. It can derail it.

This realization is something you assign meaning to. For the model there’s no difference between either of these states.

Re:Claude discovers a novel enzyme system with CRISPR-like r... by shermantanktop on Wednesday September 23, 2026 @07:43PM (#49824241)
But but but....I was told it was a stochastic parrot! I liked that idea because it appealed to my vanity, and it described the gibberish produced by older models with bad prompting, and that was enough for me thank you.

/s