Small business gets reamed on store fixtures and any sort of furniture.

Creating a market for piece work (people working at home doing small assembly / sewing / Etc functions) with folks who want to do small production runs.

Fasteners on demand, making the kinds of fasteners you want how you want them right now in reasonable quantities.

Inventory management for one/two person shops.

Phone customer support on demand.

Essential network service (DNS/Email/Web/File/Fax/Media) for small businesses. (I did this once before but its becoming more relevant, could be a 'software only' solution these days)