Biological minds in biological organisms are self referential in the way that you have a neural network that forms a model of the world. That model then "discovers" that it is "it self a part of the world" so it tries to model that part of the world (model it self). In this way some type of self referential "awareness" (or whatever you want to call it) is formed. That self model that contains awareness is then used to guide organisms behaviour. Causal Transformer LLMs don't work in this way, they have theoretical knowledge that they exist but its selfhood is not in this described way built on the self modelling that biological brains do.

All this being an empirically unproven theory/hypothesis. But an extremely strong one (if you ask me).