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A comment on Paternal metformin use associated with major birth defects (2022).

Re:Paternal metformin use associated with major birth defect... by j2j8 on Sunday July 26, 2026 @12:52AM (#49054845)
That makes sense. Metformin is used as a testosterone lowering drug for feminizing masculine females with PCOS. If it's strong enough to help get rid of a beard on a very hairy woman, it's probably going to do something to a male even though they might otherwise have more testosterone to spare.
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Re:Paternal metformin use associated with major birth defect... by inigyou on Sunday July 26, 2026 @06:36AM (#49056648)
Things that lower sperm count don't usually cause birth defects AFAIK
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