Nowadays they have macro programs to help with this that use LUA or custom scripting languages to run the game.

I remember learning LUA by writing scripts. Probably my pinnacle here was one to harvest wood / mine automatically, recalling to a bank to drop everything off and then head to a new mine, rotating mines so they wouldn't run out and playing a siren noise and sending me an email when the anti-macro popup would come up.

At this point I was more playing to see how advanced and resilient I could make my script, and less so to play the game, heh.