How to sequence your own DNA at home

Re:How to sequence your own DNA at home by Jules-Bertholet on Monday July 06, 2026 @09:12PM (#48812532)

Oxford Nanopore unfortunately has a high error rate (3-5%) compared to other sequencing technologies. And the errors are non-random

[ Parent | on HN ]

Re:How to sequence your own DNA at home by Gethsemane on Tuesday July 07, 2026 @05:16AM (#48815364)

For most DNA it now sits at ~Q20 (1%) which is a big improvement - there was also some hacky stuff like HERRO and duplex sequencing which improved it substantially. For routine genome sequencing it's definitely suitable, and the long-read advantage helps resolve some of those trickier regions

[ Parent | on HN ]

Re:How to sequence your own DNA at home by mbeavitt on Tuesday July 07, 2026 @06:24AM (#48815848)

This is simply not true, advances in basecalling and using Duplex give you >Q25

[ Parent | on HN ]