Re:GLP-1 drugs led to weight loss and reversed depression-li...
by estearum on Sunday June 28, 2026 @10:16AM
(#48707475)
> Because it's pretty likely some of these have negative long term effects. And some of those long-term effects are probably pretty serious.
No, it's really not "pretty likely." These drugs are extremely well studied, have been for a long time across now hundreds of thousands of clinical trial participants over decades.
The downsides of obesity however are immense. Far, far worse than people intuit.
Agreed non-pharmaceutical interventions are preferable when they work. But it turns out – empirically – that it's very hard to implement these successfully.
No, it's really not "pretty likely." These drugs are extremely well studied, have been for a long time across now hundreds of thousands of clinical trial participants over decades.
The downsides of obesity however are immense. Far, far worse than people intuit.
Agreed non-pharmaceutical interventions are preferable when they work. But it turns out – empirically – that it's very hard to implement these successfully.