Re:GLP-1 drugs led to weight loss and reversed depression-li...
by yakz on Saturday June 27, 2026 @07:33PM
(#48702851)
I think it'd be more accurate to say that informing people that they should change their behavior doesn't work. A person changing their behavior can escape obesity. The reality is that most people won't be able to change their behavior without some other kind of assistance.
Re:GLP-1 drugs led to weight loss and reversed depression-li...
by topgrain2 on Saturday June 27, 2026 @09:12PM
(#48703366)
Even with extensive assistance (which is way too expensive to widely deploy) outcomes are weak.
Last I checked, researchers in the specific area of high-touch weight interventions were excited that they finally had a tool that might more-than-barely work… in glp-1 agonists.
Re:GLP-1 drugs led to weight loss and reversed depression-li...
by yakz on Saturday June 27, 2026 @09:38PM
(#48703508)
I didn’t mean to suggest that GLP-1s don’t count as assistance.
Informing people that they can avoid pregnancy and STDs if they’d just stop fucking each other doesn’t work at scale either.
Think about how we describe contraceptives, medically speaking: a failure rate is tracked and promoted that’s the in the wild rate of failure, not the ideal-use rate of failure (which can be effectively zero!). The diet and exercise equivalent of a contraceptive couldn’t be sold, because its failure rate would be way higher than its success rate.
So “we” (people who’ve paid attention to the science on it) know it doesn’t work (on a population level), like for-sure definitely does not work, but a person reads this assertion of fact and goes “but wait it worked for me, this person must be dumb or something” but that’s not it. It’s two different perspectives on what it means for it to “work”.